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Viral hepatitis · 4 min read

Hepatitis B and C: not the same

They share a name and an organ, and that is where the similarity ends. One is controlled, the other is cured.

In short

  • A positive screening test needs a second test to confirm the infection is active.
  • Chronic hepatitis B is usually controlled with long-term tablets, not cured.
  • Hepatitis C is cured in more than 95% of people with a short course of tablets.

Why the mix-up matters

Patients often arrive having been told, or having read, that “hepatitis” is one thing. Then they are either terrified by a hepatitis C diagnosis that is very likely curable, or relaxed about a hepatitis B infection that needs lifelong attention. Knowing which virus you have changes everything about the plan.

Hepatitis B: control

Hepatitis B settles into the liver cells and, in most adults who carry it long-term, cannot be fully removed with current medicines. What can be done is to keep the virus suppressed. Some people need a daily antiviral tablet to do that; many only need a check-up every six to twelve months to make sure the virus is staying quiet and the liver is not being damaged.

The vaccine prevents it. Family members of anyone with hepatitis B should be tested and, if not already immune, vaccinated.

Hepatitis C: cure

A positive antibody test means you have met the virus. About a quarter of people clear it on their own; the rest carry it. A second test, HCV RNA, shows whether the virus is still active. If it is, a course of direct-acting antiviral tablets for 8 to 12 weeks cures more than 95% of people, according to the WHO. The side effects are generally mild. A test three months after the course confirms the cure.

There is no vaccine for hepatitis C. The protection is safe needles and screened blood.

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